Angiotensin-(1-7) and Its Effects in the Kidney

@inproceedings{Dilauro2009Angiotensin17AI,
  title={Angiotensin-(1-7) and Its Effects in the Kidney},
  author={Marc Dilauro and Kevin D. Burns},
  booktitle={TheScientificWorldJournal},
  year={2009}
}
Angiotensin-(1-7) (Ang-[1-7]) is a heptapeptide member of the renin-angiotensin system (RAS), and acts as a vasodilator and antagonist of angiotensin II (Ang II) in the vasculature. The role of Ang-(1-7) in regulating kidney function is not well understood. Within the kidneys, Ang-(1-7) is generated by angiotensin-converting enzyme 2 (ACE2)-mediated degradation of Ang II, sequential cleavage of the precursor angiotensin I (Ang I) by ACE2 and ACE, or the actions of brush-border membrane… CONTINUE READING
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