Angiotensin-(1-7) and Its Effects in the Kidney

  title={Angiotensin-(1-7) and Its Effects in the Kidney},
  author={Marc Dilauro and Kevin D. Burns},
Angiotensin-(1-7) (Ang-[1-7]) is a heptapeptide member of the renin-angiotensin system (RAS), and acts as a vasodilator and antagonist of angiotensin II (Ang II) in the vasculature. The role of Ang-(1-7) in regulating kidney function is not well understood. Within the kidneys, Ang-(1-7) is generated by angiotensin-converting enzyme 2 (ACE2)-mediated degradation of Ang II, sequential cleavage of the precursor angiotensin I (Ang I) by ACE2 and ACE, or the actions of brush-border membrane… CONTINUE READING
36 Extracted Citations
93 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 36 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 93 references

Similar Papers

Loading similar papers…