Angiotensin-(1-7): cardioprotective effect in myocardial ischemia/reperfusion.

  title={Angiotensin-(1-7): cardioprotective effect in myocardial ischemia/reperfusion.},
  author={A. J. Ferreira and Robson Augusto Sousa dos Santos and Alvair Pinto de Almeida},
  volume={38 3 Pt 2},
In this study we evaluate the effects of angiotensin-(1-7) on reperfusion arrhythmias in isolated rat hearts. Rat hearts were perfused according to Langendorff technique and maintained in heated (37+/-1 degrees C) and continuously gassed (95% O(2)/5% CO(2)) Krebs-Ringer solution at constant pressure (65 mm Hg). The electrical activity was recorded with an ECG (bipolar). Local ischemia was induced by coronary ligation for 15 minutes. After ischemia, hearts were reperfused for 30 minutes. Cardiac… CONTINUE READING
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