Angiostatic treatment of neuroblastoma.

  title={Angiostatic treatment of neuroblastoma.},
  author={Erik Wassberg and R Christofferson},
  journal={European journal of cancer},
  volume={33 12},
The growth of solid tumours has been shown to be dependent on new blood vessel formation, i.e. angiogenesis. Several steps in the metastatic process have also been found to be angiogenesis dependent. The mediators of tumour angiogenesis are now being elucidated, and angiostatic agents have been developed. Some of these agents are currently undergoing clinical trials. In addition to inhibition of angiogenesis, two other clinical applications of angiogenetic research in tumour diseases are… CONTINUE READING

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