Angiostatic effect of CXCR3 expressed on choroidal neovascularization.

@article{Fujimura2012AngiostaticEO,
  title={Angiostatic effect of CXCR3 expressed on choroidal neovascularization.},
  author={Shigeto Fujimura and Hidenori Takahashi and Kentaro Yuda and Takashi Ueta and Aya Iriyama and Tatsuya Inoue and Toshikatsu Kaburaki and Yasuhiro Tamaki and Kouji Matsushima and Yasuo Yanagi},
  journal={Investigative ophthalmology & visual science},
  year={2012},
  volume={53 4},
  pages={1999-2006}
}
PURPOSE Several recent studies suggest that some chemokines/chemokine receptors are involved in choroidal neovascularization (CNV). CXCR3 was the focus of the present study because microarray analysis for murine laser-induced CNV model showed the increased expression of CXCR3. The purpose of this study was to evaluate the effect of CXCR3 on CNV. METHODS Microarray analysis was performed for the mouse eyes with laser-induced CNV. CXCR3 expressions on the CNV were evaluated by… CONTINUE READING
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CCR3 is a target for agerelated macular degeneration diagnosis and therapy

A Takeda, JZ Baffi, ME Kleinman
Nature • 2009

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