Angiosarcoma successfully treated with liver transplantation and sirolimus.

  title={Angiosarcoma successfully treated with liver transplantation and sirolimus.},
  author={Megan M Xue and Prakash S. Masand and Patrick S. Thompson and Milton L Finegold and Daniel H Leung},
  journal={Pediatric transplantation},
  volume={18 4},
Malignant liver tumors represent approximately 1% of malignancies in children. HA is a high-grade tumor of endothelial cells that is even more rare in the pediatric population. HA has a limited response to chemotherapy, radiation and resection with universal tumor recurrence with LT and nearly 100% mortality by 18 months. This is the first reported successful case of hepatic angiosarcoma in a child who was treated by LT in combination with sirolimus. Sirolimus antagonizes the mTOR pathway… CONTINUE READING
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