Angiopoietin-Like Proteins: A Comprehensive Look

  title={Angiopoietin-Like Proteins: A Comprehensive Look},
  author={Gaetano Santulli},
  booktitle={Front. Endocrinol.},
Angiopoietin-like proteins (ANGPTLs) are a family of proteins structurally similar to the angiopoietins. To date, eight ANGPTLs have been discovered, namely ANGPTL1 to ANGPTL8. Emerging evidence implies a key role for ANGPTLs in the regulation of a plethora of physiological and pathophysiological processes. Most of the ANGPTLs exhibit multibiological properties, including established functional roles in lipid and glucose metabolism, inflammation, hematopoiesis, and cancer. This report… CONTINUE READING
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