Angiopoietin-2 facilitates vascular endothelial growth factor-induced angiogenesis in the mature mouse brain.

@article{Zhu2005Angiopoietin2FV,
  title={Angiopoietin-2 facilitates vascular endothelial growth factor-induced angiogenesis in the mature mouse brain.},
  author={Yiqian Zhu and Chanhung Z. Lee and Fanxia Shen and Rose Du and William Lee Young and Guo-Yuan Yang},
  journal={Stroke},
  year={2005},
  volume={36 7},
  pages={
          1533-7
        }
}
BACKGROUND AND PURPOSE A better understanding of angiogenic factors and their effects on cerebral angiogenesis is necessary for the development of effective therapeutic strategies for ischemic brain injury. Vascular endothelial growth factor (VEGF) has been shown to induce angiogenesis in the adult mouse brain. However, the function of angiopoietin-2 (Ang-2) in cerebral angiogenesis has not been clarified. The goal of this study was to identify the combined effects of VEGF and Ang-2 on cerebral… CONTINUE READING

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