Angiopoietin-1 production in islets improves islet engraftment and protects islets from cytokine-induced apoptosis.

@article{Su2007Angiopoietin1PI,
  title={Angiopoietin-1 production in islets improves islet engraftment and protects islets from cytokine-induced apoptosis.},
  author={Dongming Su and Nan Zhang and Jing Jing He and Shen Qu and Sandra Slusher and Rita Bottino and Suzanne Bertera and Jonathan S. Bromberg and H. Henry Dong},
  journal={Diabetes},
  year={2007},
  volume={56 9},
  pages={2274-83}
}
Successful islet transplantation depends on the infusion of sufficiently large quantities of islets, but only a small fraction of implanted islets become engrafted. The underlying mechanisms remain elusive. To probe the mechanism of islet revascularization, we determined the effect of angiopoietin-1 (Ang-1), a proangiogenic and antiapoptotic factor, on the survival, function, and revascularization of transplanted islets using a syngeneic model. Islets were transduced with adenoviruses… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

Luteolin prevents uric acid-induced pancreatic β-cell dysfunction

Journal of biomedical research • 2014
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 66 references

Angiogenic capacity of endothelial cells in islets of Langerhans.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology • 2003
View 4 Excerpts
Highly Influenced

Lymphatic vessels in pancreatic islets implanted under the renal capsule of rats.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons • 2006
View 1 Excerpt

Similar Papers

Loading similar papers…