Angiomotin promotes renal epithelial and carcinoma cell proliferation by retaining the nuclear YAP


Renal cell carcinoma (RCC) is one of the common tumors in the urinary system without effective therapies. Angiomotin (Amot) can interact with Yes-associated protein (YAP) to either stimulate or inhibit YAP activity, playing a potential role in cell proliferation. However, the role of Amot in regulating the proliferation of renal epithelial and RCC cells is… (More)
DOI: 10.18632/oncotarget.7161