Angiolymphoid hyperplasia with eosinophilia on penis in HIV-positive patient: an unusual presentation.


Lucio phenomenon occurs in diffuse, non-nodular form of lepromatous leprosy, chiefly encountered in Mexicans and is seen in untreated patients. Bullae may appear in the center of purpuric, painful, red patches as lucio phenomenon which was ruled out in our patients by presence of fever, nodular lesions, and by absence of purpuric lesions. Lazarine leprosy was described as a type of leprosy in either pole presenting predominantly as bullous and necrotic lesions with generalized infiltrates, loss of eyebrows, fever, gangrene and scarring. Histopathology shows infiltration of neutrophils with marked dilatation, necrosis and thrombosis of capillaries. Our patients didn’t show this kind of clinical and his to pathological features. Bullous lesions may appear on distal extremities in leprosy patients when exposed to heat because of impaired reflex dilatation of skin capillaries due to damaged dermal nerves. Clinical features, nerve involvement, AFB positivity and histopathological features in our patients suggested the final diagnosis of necrotic ENL (with bullous lesions). In severe type of ENL reaction, ulceration may occur because of necrotizing vasculitis. Vesiculobullous, ulcerated, pustular, hemorrhagic and erythema multiforme like lesions have been reported in ENL.[1-3]

DOI: 10.4103/0378-6323.104683

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@article{Damle2013AngiolymphoidHW, title={Angiolymphoid hyperplasia with eosinophilia on penis in HIV-positive patient: an unusual presentation.}, author={Dhananjay K Damle and Snehal S Raotole and Vasudha Abhijit Belgaumkar and Chandrakant B Mhaske}, journal={Indian journal of dermatology, venereology and leprology}, year={2013}, volume={79 1}, pages={109-11} }