[Angiography of the ocular fundus without dye: Optical coherence tomography based angiography in exsudative age-related macular degeneration].

Abstract

INTRODUCTION Vascular endothelial growth factor antibody therapy is an established treatment of exsudative age-related macular degeneration. AIM The morphologic characterisation of the macular microvasculature after longstanding treatment. METHOD Forty-eight patients (34 women and 14 men; age, 74.4 ± 8.0 years) were enrolled in the study. During follow-up time (53.8 ± 31.0 months), 7.6 ± 4.9 injections were administered in 56 eyes. Optical coherence tomography angiographic examination was performed with AngioVue (Optovue Inc. Fremont, CA, USA). RESULTS Distortion of the superficial retinal plexus and foveal avascular zone enlargement were noted in 5/56 eyes, deep retinal plexus defect was detected in 9/56 cases. Destruction of the choriocapillaries and the former neovascularisation could be found in 4 different patterns: 1. pigment epithelium and choriocapillary atrophy, 2. submacular scar, 3. active leaking choroidal neovascularisation, 4. intraretinal cysts. CONCLUSION Optical coherence tomography angiography is a novel non-invasive method, which enables the follow up of macular degeneration. Orv. Hetil., 2016, 157(42), 1683-1690.

Cite this paper

@article{Resch2016AngiographyOT, title={[Angiography of the ocular fundus without dye: Optical coherence tomography based angiography in exsudative age-related macular degeneration].}, author={Mikl{\'o}s D{\'e}nes Resch and Csilla N{\'e}meth and Gy{\"{o}rgy Barcsay and M{\'o}nika Ecsedy and {\'A}gnes Borb{\'a}ndy and Zsuzsanna G{\'e}hl and Anik{\'o} Balogh and Antal Szab{\'o} and Zolt{\'a}n Zsolt Nagy and Andr{\'a}s Papp}, journal={Orvosi hetilap}, year={2016}, volume={157 42}, pages={1683-1690} }