"Angiographic late catch-up" phenomenon after sirolimus-eluting stent implantation.

Abstract

BACKGROUND Although several randomized trials have shown that sirolimus-eluting stent (SES) substantially reduces in-stent restenosis, recent studies have suggested the possibility of late catch-up after SES implantation. We investigated long-term angiographic outcomes after SES implantation in real-world practice. METHODS This study was conducted on 195 patients with 253 lesions who underwent the first and long-term angiographic follow-up after SES implantation. First follow-up was done at near 6 months after SES implantation. Long-term angiographic follow-up was defined as that performed at least 36 months after index procedure. Angiographies in patients who experienced target lesion revascularization at the time of the first angiographic follow-up were excluded from the current analysis. RESULTS Minimal luminal diameter at long-term angiographic follow-up was significantly smaller compared with that at the first follow-up (2.21 ± 0.65 vs. 2.40 ± 0.55, p<0.001). In-stent late lumen loss between the first and long-term follow-up tended to be larger compared with that between SES implantation and the first follow-up (0.19 ± 0.47 vs. 0.15 ± 0.39, p=0.298). There was a trend for increased incidence of coronary artery aneurysm (1.6% and 7.5% at the first and long-term follow-up) and stent fracture (4.3% and 10.3%). Two stent aneurysms and one stent fracture were related with definite very late stent thrombosis. CONCLUSION An "angiographic late catch-up" phenomenon and a trend toward increased incidence of coronary artery aneurysm and stent fracture were found at a median 46.5-month angiographic follow-up compared with a median 6-month follow-up.

DOI: 10.1016/j.ijcard.2011.03.024

Statistics

010020030020132014201520162017
Citations per Year

98 Citations

Semantic Scholar estimates that this publication has 98 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Yang2012AngiographicLC, title={"Angiographic late catch-up" phenomenon after sirolimus-eluting stent implantation.}, author={Tae-hyun Yang and Doo-il Kim and Han-Young Jin and Young-Wan Cho and Sang Ryul Chung and Dong-Kie Kim and Y Kim and Jae-Sik Jang and Ung Kim and Sang-hoon Seol and Dae-Kyeong Kim and Dong-Soo Kim}, journal={International journal of cardiology}, year={2012}, volume={160 1}, pages={48-52} }