Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early rheumatoid arthritis: an observational study

@inproceedings{Kelly2015AngiogenicGE,
  title={Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early rheumatoid arthritis: an observational study},
  author={Stephen G Kelly and Michele Bombardieri and Frances Humby and Nora Ng and Alessandra Marrelli and Sudeh Riahi and Maria DiCicco and Arti Mahto and Lu Zou and Debasish Pyne and Rebecca Eve Hands and Costantino Pitzalis},
  booktitle={Arthritis research & therapy},
  year={2015}
}
INTRODUCTION Neovascularization contributes to the development of sustained synovial inflammation in the early stages of Rheumatoid Arthritis. Ultrasound (US) provides an indirect method of assessing synovial blood flow and has been shown to correlate with clinical disease activity in patients with Rheumatoid Arthritis. This study examines the relationship of US determined synovitis with synovial vascularity, angiogenic/lymphangiogenic factors and cellular mediators of inflammation in a cohort… CONTINUE READING