Angiogenesis induced by tumor necrosis factor-agr; is mediated by α4 integrins

Abstract

Tumor necrosis factor-α (TNF-α) and fibroblast growth factor-2 (FGF-2 or bFGF) are potent stimulators of angiogenesis. TNF-α, but not FGF-2, can induce the expression of vascular cell adhesion molecule-1 (VCAM-1) on the surface of endothelial cells. The soluble form of VCAM-1 has recently been demonstrated to function as an angiogenic mediator. Here we… (More)
DOI: 10.1023/A:1009296700991

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Cite this paper

@article{Vanderslice2004AngiogenesisIB, title={Angiogenesis induced by tumor necrosis factor-agr; is mediated by α4 integrins}, author={Peter Vanderslice and Christy L. Munsch and Eugene Rachal and David Erichsen and Kay M. Sughrue and Ann N. Truong and James N. Wygant and Bradley W. McIntyre and Suzanne G. Eskin and Ronald G. Tilton and Peter J. Polverini}, journal={Angiogenesis}, year={2004}, volume={2}, pages={265-275} }