Angiogenesis in cervical cancer is mediated by HeLa metabolites through endothelial cell tissue kallikrein.

@article{Naidoo2009AngiogenesisIC,
  title={Angiogenesis in cervical cancer is mediated by HeLa metabolites through endothelial cell tissue kallikrein.},
  author={Strinivasen Naidoo and Deshandra Munsamy Raidoo},
  journal={Oncology reports},
  year={2009},
  volume={22 2},
  pages={285-93}
}
High vascularity correlates with poor clinical outcome in cancer of the uterine cervix. We investigated whether human cervical cancer cell (HeLa) metabolites influenced endothelial cell proliferation through the serine protease, tissue kallikrein. The angiogenic potential of tissue kallikrein is proposed due to its proteolytic, mitogenic and invasive… CONTINUE READING