Angiogenesis in atherosclerosis: gathering evidence beyond speculation.

@article{Moulton2006AngiogenesisIA,
  title={Angiogenesis in atherosclerosis: gathering evidence beyond speculation.},
  author={Karen S. Moulton},
  journal={Current opinion in lipidology},
  year={2006},
  volume={17 5},
  pages={
          548-55
        }
}
PURPOSE OF REVIEW The present review summarizes evidence for several functions of neovascularization in plaque growth that sustain perfusion beyond limits of diffusion from the artery lumen and outer adventitial vasa vasorum, deposit proatherogenic plasma molecules, recruit immune cells and progenitors, and promote intraplaque hemorrhage. Recent approvals of antiangiogenesis drugs for clinical use in cancer and macular degeneration improve the feasibility of testing whether such agents inhibit… CONTINUE READING

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