Angiogenesis in acute and chronic leukemias.

  title={Angiogenesis in acute and chronic leukemias.},
  author={D. J. H. Dickson and Paul J. Shami},
  journal={Leukemia & lymphoma},
  volume={42 5},
Angiogenesis plays a key role in the growth of solid tumors. More recently, accumulating evidence has linked angiogenesis to the pathophysiology of leukemias. Different investigators have shown evidence of increased angiogenesis in the bone marrows of patients with acute and chronic leukemias. Elevated levels of angiogenic factors have also been reported in leukemic patients. A potential role for VEGF as an autocrine growth factor in AML has been suggested. Studies on the role of angiogenesis… CONTINUE READING
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