Angiogenesis in a delayed revascularization model is accelerated by angiogenic oligosaccharides of hyaluronan.

@article{Lees1995AngiogenesisIA,
  title={Angiogenesis in a delayed revascularization model is accelerated by angiogenic oligosaccharides of hyaluronan.},
  author={Vivien C. Lees and T P David Fan and David C. West},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1995},
  volume={73 2},
  pages={259-66}
}
BACKGROUND A delayed revascularisation model has been used to assess the angiogenic activity of hyaluronan fragments on impaired wound healing. EXPERIMENTAL DESIGN Revascularisation of single, full thickness skin autografts in rats was delayed by subjecting isolated grafts to a sublethal cryoinjury (freeze injury) before implantation. Hyaluronan fragments were delivered to the grafts using slow release pellets (ethylene vinyl acetate copolymer). Rates of release were measured in vitro by… CONTINUE READING

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