Angiogenesis as targeted breast cancer therapy.

  title={Angiogenesis as targeted breast cancer therapy.},
  author={Daniel F. Hayes and Kathy D. Miller and George W. Sledge},
  volume={16 Suppl 2},
Neo-angiogenesis appears to be a critical feature of tumor growth, migration, and metastasis. Therefore, inhibition of angiogenesis is an appealing strategy for treatment of cancer. Since angiogenesis is the result of several mechanistic processes, controlled by numerable pro- and anti-angiogenic factors and their receptors, multiple possibilities to prevent or reverse tumor-induced neo-vascularization have been proposed. Of these, currently, the most promising approach has been the use of… CONTINUE READING


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