Angiogenesis and vasculogenesis in rheumatoid arthritis.

  title={Angiogenesis and vasculogenesis in rheumatoid arthritis.},
  author={Zolt{\'a}n Szekanecz and Timea Besenyei and {\'A}gnes Szentp{\'e}tery and Alisa Erika Koch},
  journal={Current opinion in rheumatology},
  volume={22 3},
PURPOSE OF REVIEW Angiogenesis is the formation of new capillaries from pre-existing vessels, whereas vasculogenesis is de-novo capillary formation from endothelial precursor cells (EPCs). Current understanding of the role of angiogenesis and vasculogenesis in rheumatoid arthritis (RA) and possibilities of therapeutic intervention should be summarized. RECENT FINDINGS There have been many recent studies on the role of the hypoxia and hypoxia-inducible factor (HIF)-vascular endothelial growth… CONTINUE READING