Angiogenesis and vascular malformations: antiangiogenic drugs for treatment of gastrointestinal bleeding.

@article{Bauditz2007AngiogenesisAV,
  title={Angiogenesis and vascular malformations: antiangiogenic drugs for treatment of gastrointestinal bleeding.},
  author={Juergen Bauditz and Herbert Lochs},
  journal={World journal of gastroenterology},
  year={2007},
  volume={13 45},
  pages={5979-84}
}
Treatment of gastrointestinal bleeding in patients with angiodysplasias and Osler's disease (hereditary hemorrhagic teleangiectasia) is clinically challenging. Frequently, vascular malformations occur as multiple disseminated lesions, making local treatment an unfavorable choice or impossible. After local therapy, lesions often recur at other sites of the intestine. However, as there are few therapeutic alternatives, repeated endoscopic coagulations or surgical resections are still performed to… CONTINUE READING