Angiogenesis: a curse or cure?

  title={Angiogenesis: a curse or cure?},
  author={Kalpna Gupta and Jian Gong Zhang},
  journal={Postgraduate medical journal},
  volume={81 954},
Angiogenesis, the growth of new blood vessels is essential during fetal development, female reproductive cycle, and tissue repair. In contrast, uncontrolled angiogenesis promotes the neoplastic disease and retinopathies, while inadequate angiogenesis can lead to coronary artery disease. A balance between pro-angiogenic and antiangiogenic growth factors and cytokines tightly controls angiogenesis. Considerable progress has been made in identifying these molecular components to develop… CONTINUE READING