Angiogenesis, adipokines and breast cancer.

  title={Angiogenesis, adipokines and breast cancer.},
  author={Linda Vona-Davis and David P. Rose},
  journal={Cytokine & growth factor reviews},
  volume={20 3},
The prevalence of overweight and obesity is rapidly increasing world wide. Numerous epidemiological studies have shown that obesity is a risk factor for postmenopausal breast cancer and relapse. However, the biological factors that drive the growth and progression of these tumors and how obesity contributes to the tumor microenvironment are poorly understood. Tumor development and metastasis are dependent on the process of angiogenesis or the formation of new blood vessels. More importantly, a… CONTINUE READING


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