Angioblast-mesenchyme induction of early kidney development is mediated by Wt1 and Vegfa.


Most studies on kidney development have considered the interaction of the metanephric mesenchyme and the ureteric bud to be the major inductive event that maintains tubular differentiation and branching morphogenesis. The mesenchyme produces Gdnf, which stimulates branching, and the ureteric bud stimulates continued growth of the mesenchyme and… (More)


8 Figures and Tables