Angioadaptation: keeping the vascular system in shape.

  title={Angioadaptation: keeping the vascular system in shape.},
  author={Andreas Zakrzewicz and Timothy W. Secomb and Axel Radlach Pries},
  journal={News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society},
The development and maintenance of the vascular system requires not only the formation of new vessels (vasculogenesis, angiogenesis) but also the continuous adjustment of vessel and network structures in response to functional needs. This "angioadaptation" depends on the interplay of vascular responses to growth factors, to the metabolic status of the tissue, and to hemodynamic forces exerted by the flowing blood.