Angina, ischemia, and effort tolerance with vasodilating beta-blockers.

@article{Dargie1991AnginaIA,
  title={Angina, ischemia, and effort tolerance with vasodilating beta-blockers.},
  author={Henry J. Dargie and Stanley Grant and James M. McLenachan},
  journal={American heart journal},
  year={1991},
  volume={121 3 Pt 2},
  pages={1017-20}
}
beta-Blockers are known to suppress exercise-induced ischemia but give rise to such problems as fatigue or dyspnea on effort and also bradycardia. In a series of double-blind, placebo-controlled studies of celiprolol (a cardioselective beta 1-blocker with beta 2-agonist and vasodilatory properties) in patients with hypertension and angina and in normal… CONTINUE READING