Angela R.: a familial Alzheimer’s disease case in the days of Auguste D.


The rebuilding of the N family, a large Italian kindred affected by early-onset autosomal dominant Alzheimer’s disease (AD), provided an important contribution to the discovery of Presenilin 1 (PSEN1), the main gene responsible for familial AD. This pedigree was identified with the help of medical records from the archives of the Psychiatric Hospital of… (More)
DOI: 10.1007/s00415-016-8294-x


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