AngII induces HepG2 cells to activate epithelial-mesenchymal transition

@inproceedings{Qi2018AngIIIH,
  title={AngII induces HepG2 cells to activate epithelial-mesenchymal transition},
  author={Minghua Qi and Yuanping Zhou and Jikui Liu and Xi Yang Ou and Minghua Li and Xia Long and Jing Ye and Guangyin Yu},
  booktitle={Experimental and therapeutic medicine},
  year={2018}
}
The present study aimed to determine whether HepG2 can induce epithelial-mesenchymal transition (EMT) via angiotensin II (AngII) simulation. The expression levels of EMT markers vimentin and E-cadherin in cancer tissues and adjacent tissues of patients with hepatocellular carcinoma (HCC) were detected by immunohistochemistry. In addition, HepG2 cells were stimulated with AngII, and the gene and protein expression levels of vimentin and E-cadherin were measured by reverse transcription… CONTINUE READING
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