Aneurysm Repair in a Patient With Systemic Mastocytosis.

  title={Aneurysm Repair in a Patient With Systemic Mastocytosis.},
  author={Neal M Duggal and Erin K. Payne and Milo Engoren},
  journal={Journal of cardiothoracic and vascular anesthesia},
  volume={29 4},
1 or more organs. It carries profound perioperative implications as various stimuli and medications can result in anaphylaxis. However, anaphylaxis from mastocytosis is different from IgEmediated hypersensitivity anaphylaxis, in that the precipitating agent directly activates mast cells without IgE mediation. The authors report the successful perioperative management of a patient with undiagnosed systemic mastocytosis complicated by undiagnosed drug-induced IgE hypersensitivity.