Anesthetics and sedatives: toxic or protective for the developing brain?

  title={Anesthetics and sedatives: toxic or protective for the developing brain?},
  author={Christopher G Ward and Andreas W. Loepke},
  journal={Pharmacological research},
  volume={65 3},
Despite our insufficient understanding of the exact molecular mechanisms of general anesthetics and sedatives, every year millions of children are treated with these drugs in a seemingly safe manner. However, increasing evidence particularly from animal studies has suggested the possibility for deleterious effects in pediatric patients. All currently clinically utilized anesthetic drugs have been found to induce neuronal cell death in the developing brain and to potentially cause long-term… CONTINUE READING
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