Anesthetics affect the uptake but not the depolarization-evoked release of GABA in rat striatal synaptosomes.

@article{Mantz1995AnestheticsAT,
  title={Anesthetics affect the uptake but not the depolarization-evoked release of GABA in rat striatal synaptosomes.},
  author={Jean Mantz and J B Lecharny and Vincent Laudenbach and David Henzel and Gilles Peytavin and Jean Marie Desmonts},
  journal={Anesthesiology},
  year={1995},
  volume={82 2},
  pages={502-11}
}
BACKGROUND Numerous classes of anesthetic agents have been shown to enhance the effects mediated by the postsynaptic gamma-aminobutyric acid A (GABAA) receptor-coupled chloride channel in the mammalian central nervous system. However, presynaptic actions of anesthetics potentially relevant to clinical anesthesia remain to be clarified. Therefore, in this study, the effects of intravenous and volatile anesthetics on both the uptake and the depolarization-evoked release of GABA in the rat… CONTINUE READING
21 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…