Anesthetic state does not affect the map of the hand representation within area 3b somatosensory cortex in owl monkey

  title={Anesthetic state does not affect the map of the hand representation within area 3b somatosensory cortex in owl monkey},
  author={Michael P. Stryker and William M. Jenkins and M. M. Merzenich},
  journal={Journal of Comparative Neurology},
Receptive fields defined for small clusters of neurons within the middle cortical layers of area 3b differed little in size or in the skin locations represented among: (a) alert, (b) nitrous oxide‐anesthetized, (c) deep sodium pentobarbital‐anesthetized, and (d) ketamine‐anesthetized owl monkeys. Repeated recordings from nearly identical cortical loci yielded nearly identical multiunit receptive fields under different conditions of anesthesia. 

Optical imaging of digit topography in individual awake and anesthetized squirrel monkeys

Intensive signal optical imaging in alert monkeys was used to examine the spatial specificity of cortical topographic representation and found larger cortical activation sizes in the alert animal in area 3b, where activation widths were found to overlap with even non-adjacent digits.

Optical Imaging of SI Topography in Anesthetized and Awake Squirrel Monkeys

Differences in relative dominance of area 3b versus area 1 suggest that inter-areal interactions in the alert animal differ substantially from that in the anesthetized animal and brings into question the role of a precise topographic map during behavior.

Topographic reorganization of the hand representation in cortical area 3b owl monkeys trained in a frequency-discrimination task.

Adult owl monkeys were trained to detect differences in the frequency of a tactile flutter-vibration stimulus above a 20-Hz standard and the cortical representations of the trained hands were substantially more complex in topographic detail than the representations of unstimulated hands or of passively stimulated control hands.

Functional reorganization of primary somatosensory cortex in adult owl monkeys after behaviorally controlled tactile stimulation.

These experiments demonstrate that functional cortical remodeling of the S1 koniocortical field, area 3b, results from behavioral manipulations in normal adult owl monkeys.

Responses of barrel cortex neurons in awake rats and effects of urethane anesthesia

Results in the awake condition confirm those of previous studies conducted in unanesthetized or lightly sedated animals, and data obtained withUrethane are comparable to others' results in urethane-anesthenized rats, with important implications for how barrel cortex processes information in behaving animals.

Changes in the distributed temporal response properties of SI cortical neurons reflect improvements in performance on a temporally based tactile discrimination task.

By behaviorally training adult owl monkeys to discriminate the temporal features of a tactile stimulus, distributed spatial and temporal response properties of cortical neurons are altered.

Anesthetics Eliminate Somatosensory-Evoked Discharges of Neurons in the Somatotopically Organized Sensorimotor Striatum of the Rat

  • M. West
  • Biology
    The Journal of Neuroscience
  • 1998
The data show that somatotopically organized lateral striatal neurons stop discharging in response to natural stimulation during anesthesia, and available data indicate they do not reach threshold in Response to depolarizations produced by glutamatergic corticostriatal synaptic transmission projected from the somatosensory cortex.

Plasticity of primary somatosensory cortex paralleling sensorimotor skill recovery from stroke in adult monkeys.

Adult owl and squirrel monkeys were trained to master a small-object retrieval sensorimotor skill and revealed a postlesion reemergence of the representation of the fingertips engaged in the behavior in novel locations in two of five monkeys and a less substantial change in the representation in the hand in the intact parts of area 3b in three ofFive monkeys.

Remodelling of hand representation in adult cortex determined by timing of tactile stimulation

It is shown, using adult owl monkeys trained to respond to specific stimulus sequence events, that serial application of stimuli to the fingers results in changes to the neuronal response specificity and maps of the hand surfaces in the true primary somatosensory cortical field.

Fine-scale organization of SI (area 3b) in the squirrel monkey revealed with intrinsic optical imaging.

Cortical signals observed with intrinsic signal optical imaging delineated a somatotopic organization of area 3b of the squirrel monkey cortex and revealed different topographical cortical activation patterns for pressure, flutter, and vibratory stimuli, dependent on anesthesia type.



Somatosensory cortical map changes following digit amputation in adult monkeys

The cortical representations of the hand in area 3b in adult owl monkeys were defined with use of microelectrode mapping techniques 2–8 months after surgical amputation of digit 3, or of both digits

Double representation of the body surface within cytoarchitectonic area 3b and 1 in “SI” in the owl monkey (aotus trivirgatus)

Microelectrode multiunit mapping studies of parietal cortex in owl monkeys indicate that the classical “primary” somatosensory region (or “SI”) including the separate architectonic fields 3a, 3b, 1,

Response characteristics of single cells in the monkey superior colliculus following ablation or cooling of visual cortex.

The present study has been undertaken to investigate the contribution of visual cortex to collicular function in the rhesus monkey, a species whose visual svstem is believed to be rather similar to that of man.

Representations of the body surface in postcentral parietal cortex of Macaca fascicularis

The somatotopic organization of the postcentral parietal cortex of the Old World monkey, Macaca fascicularis, was determined with multi‐unit microelectrode recordings and it is suggested that the representation in Area 3b is homologous to “SmI” (or “SI”) in non‐primates.

Single-unit recording and stimulation in superior colliculus of the alert rhesus monkey.

The relationship between recording and stimulation data is clarified by using methods which allow a direct comparison and shows a reasonable correspondence with the receptive-field map of the superior colliculus reported by Cynader and Berman (5).

Receptive-field organization of monkey superior colliculus.

A NUMBER OF recent studies suggest that the mammalian superior colliculus plays a crucial role in visually guided behavior (33, 35). Ablation experiments indicate that lesions in the hamster superior

Variability in hand surface representations in areas 3b and 1 in adult owl and squirrel monkeys

Detailed microelectrode maps of the hand representation were derived in cortical areas 3b and 1 from a series of normal adult owl and squirrel monkeys, and all maps were internally topographic.

Functional reorganization in somatosensory cortical areas 3b and 1 of adult monkeys after median nerve repair: possible relationships to sensory recovery in humans

The results suggest that nerve regeneration reestablishes the cortical capacity to process tactile information from reinnervated skin via a prolonged reorganizational process that appears dependent on peripheral and central factors.