Anesthetic-induced improvement of the inflammatory response to one-lung ventilation.

  title={Anesthetic-induced improvement of the inflammatory response to one-lung ventilation.},
  author={Elisena de Conno and Marc P. Steurer and Moritz Wittlinger and Marco Piero Zalunardo and Walter Weder and Didier Schneiter and Ralph C. Schimmer and Richard Klaghofer and Thomas A. Neff and Edith R. Schmid and Donat R Spahn and Birgit Roth Z'graggen and Martin Urner and Beatrice Beck-Schimmer},
  volume={110 6},
BACKGROUND Although one-lung ventilation (OLV) has become an established procedure during thoracic surgery, sparse data exist about inflammatory alterations in the deflated, reventilated lung. The aim of this study was to prospectively investigate the effect of OLV on the pulmonary inflammatory response and to assess possible immunomodulatory effects of the anesthetics propofol and sevoflurane. METHODS Fifty-four adults undergoing thoracic surgery with OLV were randomly assigned to receive… CONTINUE READING


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