Anesthetic Management of Patients with Congenital Insensitivity to Pain with Anhidrosis: A Retrospective Analysis of 358 Procedures Performed Under General Anesthesia.

@article{Zlotnik2015AnestheticMO,
  title={Anesthetic Management of Patients with Congenital Insensitivity to Pain with Anhidrosis: A Retrospective Analysis of 358 Procedures Performed Under General Anesthesia.},
  author={Alexander Zlotnik and Dmitry Natanel and Ruslan Kutz and Matthew Boyko and Evgeny Brotfain and Benjamin Fredrick Gruenbaum and Shaun Even Gruenbaum and Lisa Bodner},
  journal={Anesthesia and analgesia},
  year={2015},
  volume={121 5},
  pages={1316-20}
}
BACKGROUND Congenital insensitivity to pain with anhidrosis (CIPA) is a rare autosomal recessive disorder characterized by recurrent episodic fevers, anhidrosis, absent reaction to noxious stimuli, self-mutilating behavior, and mental retardation. The anesthetic management of patients with CIPA is challenging. Autonomic nervous system abnormalities are common, and patients are at increased risk for perioperative complications. METHODS In this study, we describe our experience with 35 patients… CONTINUE READING