Anesthetic Effects of a Mixture of Medetomidine, Midazolam and Butorphanol in Two Strains of Mice

@inproceedings{Kirihara2013AnestheticEO,
  title={Anesthetic Effects of a Mixture of Medetomidine, Midazolam and Butorphanol in
Two Strains of Mice},
  author={Yumiko Kirihara and Mayumi Takechi and Kaoru Kurosaki and Yuta Kobayashi and Tsutomu Miki Kurosawa},
  booktitle={Experimental animals},
  year={2013}
}
The combination of ketamine and xylazine is a widely used anesthetic for laboratory animals. However, due to an abuse problem in Japan, ketamine has been specified as a narcotic since 2007. Instead of using ketamine, Kawai et al. reported an injectable formula with an equivalent effect to the mixture of ketamine and xylazine [11]. The mixture of 0.3 mg/kg body weight (b.w.) medetomidine (Med.), 4.0 mg/kg b.w. midazoram (Mid.), and 5.0 mg/kg b.w. butorphanol (But.) produced an anesthetic… CONTINUE READING
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