Anesthetic Depth Defined Using Multiple Noxious Stimuli during Isoflurane/Oxygen Anesthesia I. Motor Reactions

@article{Zbinden1994AnestheticDD,
  title={Anesthetic Depth Defined Using Multiple Noxious Stimuli during Isoflurane/Oxygen Anesthesia I. Motor Reactions},
  author={Alex M. Zbinden and Marco Maggiorini and Steen Petersen‐Felix and Rolf Lauber and Dick A. Thomson and C. Minder},
  journal={Anesthesiology},
  year={1994},
  volume={80},
  pages={253–260}
}
BackgroundPotency of inhaled anesthetics usually is defined by determining the minimal alveolar concentration (MAC) that prevents movement in 50% of patients in response to skin incision. Skin incision, however, is usually only a single event and, thus, determination of potency cannot be repeated in one patient. Traditional MACskin incision cannot be used to predict response to other noxious stimuli. The aim of this study was to investigate the effects of other noxious stimulation patterns and… 
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    Anesthesia and analgesia
  • 2001
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