Anesthetic Depth Defined Using Multiple Noxious Stimuli during Isoflurane/Oxygen Anesthesia I. Motor Reactions

  title={Anesthetic Depth Defined Using Multiple Noxious Stimuli during Isoflurane/Oxygen Anesthesia I. Motor Reactions},
  author={Alex M. Zbinden and Marco Maggiorini and Steen Petersen‐Felix and Rolf Lauber and Dick A. Thomson and C. Minder},
BackgroundPotency of inhaled anesthetics usually is defined by determining the minimal alveolar concentration (MAC) that prevents movement in 50% of patients in response to skin incision. Skin incision, however, is usually only a single event and, thus, determination of potency cannot be repeated in one patient. Traditional MACskin incision cannot be used to predict response to other noxious stimuli. The aim of this study was to investigate the effects of other noxious stimulation patterns and… 
Reduction by Fentanyl of the Cp50 Values of Propofol and Hemodynamic Responses to Various Noxious Stimuli
The authors successfully defined the propofol concentration required for various stimuli and Propofol used with fentanyl attenuated the systolic blood pressure increases to various noxious stimuli in a dose‐dependent fashion.
Minimum Alveolar Anesthetic Concentrations for Airway Occlusion in Cats: A New Concept of Minimum Alveolar Anesthetic Concentration-Airway Occlusion Response
Airway occlusion can be a noxious stimulus and can induce an all-or-none type of motor response, depending on the depth of inhalational anesthesia in cats, and this phenomenon can permit the introduction of a new concept of minimum alveolar anesthetic concentration airway Occlusion response.
Monitoring of Immobility to Noxious Stimulation during Sevoflurane Anesthesia Using the Spinal H-reflex
Although this does not imply a causal relation, it explains the high predictive value of H-reflex amplitude for motor responses to noxious stimuli, even in a narrow concentration range around the MACtetanus.
Determination of the minimum alveolar concentration of isoflurane in Shetland ponies using constant current or constant voltage electrical stimulation.
The MAC of isoflurane in the Shetland ponies was lower than expected with considerable variability among individuals, and Constant current surface electrode stimulations were the most repeatable.
Potency (Minimum Alveolar Anesthetic Concentration) of Isoflurane Is Independent of Peripheral Anesthetic Effects
It is concluded that the peripheral effects of isoflurane do not influence the response to a noxious stimulus, and inhaled anesthetics act in peripheral tissues, although it is unclear whether they influence anesthetic requirements.
Decrease in minimum alveolar concentration of sevoflurane during anaesthesia and arthroscopy.
It is concluded that the MACtetanus of sevoflurane decreases during anaesthesia and surgery.
Postpartum changes in the minimum alveolar concentration of isoflurane.
The minimum alveolar concentration (MAC) of isoflurane was reduced in women 24-36 h postpartum and gradually increased to normal values by 72 h post partum.
Age, Minimum Alveolar Anesthetic Concentration, and Minimum Alveolar Anesthetic Concentration-Awake
  • E. Eger
  • Medicine
    Anesthesia and analgesia
  • 2001
An algorithm that might be used to produce a display of end-tidal concentrations of inhaled anesthetics, including provision of an estimate of the effect of nitrous oxide, is provided.
Evaluation of administration of isoflurane at approximately the minimum alveolar concentration on depression of a nociceptive withdrawal reflex evoked by transcutaneous electrical stimulation in ponies.
Anesthetic-induced changes in sensory-motor processing in ponies anesthetized with isoflurane at concentrations of approximately 1.0 MAC can be detected by assessment of NWR, and this method will permit comparison of effects of inhaled anesthetics or anesthetic combinations on spinal processing in equids.