Anesthesia suppresses nonsynchronous responses to repetitive broadband stimuli.

  title={Anesthesia suppresses nonsynchronous responses to repetitive broadband stimuli.},
  author={Robert L. Rennaker and Holle L Carey and Sven E. Anderson and Andrew M Sloan and Michael P. Kilgard},
  volume={145 1},
Although many aspects of sensory processing are qualitatively similar in awake and anesthetized subjects, important state-dependent differences are known to exist. To investigate the effects of anesthesia on temporal processing in rat auditory cortex, multi-unit neural responses to trains of broadband clicks were recorded prior to, 15 min following, and 5 h following the administration of a ketamine-based anesthetic. While responses to clicks in isolation were relatively stable between states… CONTINUE READING

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