Anesthesia induction with sevoflurane and propofol: evaluation of P-wave dispersion, QT and corrected QT intervals.

Abstract

The present study compared the effects of anesthesia induction with sevoflurane and propofol on hemodynamics, P-wave dispersion (Pwd), QT interval and corrected QT (QTc) interval. A total of 72 adult patients were included in this prospective study. All patients had control electrocardiograms (ECGs) before anesthesia induction. Anesthesia was induced with sevoflurane inhalation or intravenous propofol. Electrocardiography for all patients was performed during the 1(st) and 3(rd) minutes of induction, 3 minutes after administration of muscle relaxant, and at 5 minutes and 10 minutes after intubation. Pwd and QT intervals were measured on all ECGs. QTc intervals were determined using the Bazett formula. There was no significant difference in Pwd and QT and QTc intervals on control ECGs. In the sevoflurane group, except for control ECGs, Pwd and QTc interval on all ECGs were significantly longer than those in the propofol group (p < 0.05). We conclude that propofol should be used for anesthesia induction in patients with a predisposition to preoperative arrhythmias, and in those whose Pwd and QTc durations are prolonged on preoperative ECGs.

DOI: 10.1016/S1607-551X(10)70074-7

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Cite this paper

@article{Hanci2010AnesthesiaIW, title={Anesthesia induction with sevoflurane and propofol: evaluation of P-wave dispersion, QT and corrected QT intervals.}, author={Volkan Hanci and Mustafa Aydin and B{\"{u}lent Serhan Yurtlu and Hilal Peri Ayoğlu and Rahşan Dilek Okyay and Ebru Taş and G{\"{u}lay Erdoğan and Keziban Nur Aydoğan and Işil Ozkoçak Turan}, journal={The Kaohsiung journal of medical sciences}, year={2010}, volume={26 9}, pages={470-7} }