Anesthesia considerations for the patient with progressive systemic sclerosis (scleroderma).

Abstract

Progressive systemic sclerosis, hereafter known as scleroderma, is a chronic disease of unknown etiology characterized by a widespread disturbance in connective tissue and resultant sclerosis of the skin and subcutaneous tissue, as well as alterations in various internal organs, especially the lungs, heart, gastrointestinal tract and kidneys. This uncommon disease has a worldwide distribution but is rare in Asia, especially among the Chinese, Indians, and Malaysians. The onset of the disease is usually in the third to fifth decades, and affects women twice as often as men. Hereditary factors are not involved.' The increased fibrosis in the various organ systems is considered to be due to the overproduction of collagen. 2

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Cite this paper

@article{Smoak1982AnesthesiaCF, title={Anesthesia considerations for the patient with progressive systemic sclerosis (scleroderma).}, author={L R Smoak}, journal={AANA journal}, year={1982}, volume={50 6}, pages={548-54} }