Anesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial.

@article{Collins2005AnesthesiaassistedVB,
  title={Anesthesia-assisted vs buprenorphine- or clonidine-assisted heroin detoxification and naltrexone induction: a randomized trial.},
  author={Eric D. Collins and Herbert D. Kleber and Robert A. Whittington and Nicole E Heitler},
  journal={JAMA},
  year={2005},
  volume={294 8},
  pages={903-13}
}
CONTEXT Rapid opioid detoxification with opioid antagonist induction using general anesthesia has emerged as an expensive, potentially dangerous, unproven approach to treat opioid dependence. OBJECTIVE To determine how anesthesia-assisted detoxification with rapid antagonist induction for heroin dependence compared with 2 alternative detoxification and antagonist induction methods. DESIGN, SETTING, AND PATIENTS A total of 106 treatment-seeking heroin-dependent patients, aged 21 through 50… CONTINUE READING
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