Anesthesia alters NO-mediated functional hyperemia.

  title={Anesthesia alters NO-mediated functional hyperemia.},
  author={Ronald J Gerrits and Elliot A. Stein and Andrew S. Greene},
  journal={Brain research},
  volume={907 1-2},
Many properties of nitric oxide, NO, (localization, diffusiveness, half-life, vasodilatory affects) have supported its potential role in mediating the link between local cerebral activity and blood flow. However, evidence that both supports and refutes a role for NO in functional hyperemia have been presented. The present study employed multiple nitric oxide synthase inhibitors, two anesthetic regimes and laser-Doppler flowmetry to test the hypothesis that NO is critically involved in mediating… CONTINUE READING