Anemia with chronic renal disorder and disrupted metabolism of erythropoietin in ICR-derived glomerulonephritis (ICGN) mice.

@article{YamaguchiYamada2004AnemiaWC,
  title={Anemia with chronic renal disorder and disrupted metabolism of erythropoietin in ICR-derived glomerulonephritis (ICGN) mice.},
  author={Misuzu Yamaguchi-Yamada and Noboru Manabe and Kozue Uchio-Yamada and Naotsugu Akashi and Yasufumi Goto and Youhei Miyamoto and Masaya Nagao and Yoshie Yamamoto and Atsuo Ogura and Hajime Miyamoto},
  journal={The Journal of veterinary medical science},
  year={2004},
  volume={66 4},
  pages={423-31}
}
The ICR-derived glomerulonephritis (ICGN) mouse, a new inbred mouse strain with a hereditary nephrotic syndrome, is considered to be a good model of human idiopathic nephrotic syndrome and notably exhibits proteinuria and hypoproteinemia from the neonatal stage. In chronic renal disorder (CRD), anemia is a major subsequent symptom (renal anemia). The precise cause of renal anemia remains unclear, primarily owing to the lack of appropriate spontaneous animal models for CRD. To establish adequate… CONTINUE READING
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