Androsta-2,4-diene-6,17-dione.

@article{Hanson1970Androsta24diene617dione,
  title={Androsta-2,4-diene-6,17-dione.},
  author={J. Hanson and T. Organ},
  journal={Journal of the Chemical Society. Perkin transactions 1},
  year={1970},
  volume={18},
  pages={
          2473-5
        }
}
  • J. Hanson, T. Organ
  • Published 1970
  • Chemistry, Medicine
  • Journal of the Chemical Society. Perkin transactions 1
  • Treatment of 5α,6α-epoxy-3β-methylsulphonyloxyandrostan-17-one with lithium bromide and lithium carbonate in dimethylformamide afforded androst-4-ene-6,17-dione. Dehydrogenation of this with dichlorodicyanobenzo-quinone gave androsta-2,4-diene-6,17-dione. This was also prepared by oxidation of the epoxide to the 5α-hydroxy-6-ketone followed by elimination of the methanesulphonate group with lithium carbonate and dehydration of the 5α-alcohol with thionyl chloride. 
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