• Corpus ID: 27881889

Andrographis paniculata, the Key Facts for Therapeutic Use

  title={Andrographis paniculata, the Key Facts for Therapeutic Use},
  author={S Behr and Chuan Xin Lian},
Andrographis paniculata Nees is a slender upright annual varying in height from 30 to 100 cm (1 to 3 feet), with a square stem and « lanceolate leaves » (i.e., shaped like a lance, sharp at the ends and curved in the middle). Andrographis is indigenous to the plains of India where it is called Kalmegh (in the Bengali language) or Kiryat (in the Hindi language). It is cultivated throughout Southeast Asia and in China where it is called Chuan Xin Lian, and has also been introduced to the West… 

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The results of the present study indicated that Andrographis paniculata possess hepatoprotective effects which could compromise the medicinal use of this plant in folk medicine.



Antifertility effect of Andrographis paniculata (Nees) in male albino rat.

Dry leaf powder of A. paniculata, when fed orally to male albino rats, at a dose level of 20 mg powder per day for 60 days, resulted in cessation of spermatogenesis, degenerative changes in the

Immunostimulant agents from Andrographis paniculata.

The stimulation of both antigen specific and nonspecific immune response was, however, of lower order with andrographolide than with the EtOH extract, suggesting thereby that substance(s) other than andrograpolide present in the extract may also be contributing towards immunostimulation.

Undetectable anti-bacterial activity of Andrographis paniculata (Burma) wall. ex ness.

It is found that anti-bacterial activity of AP is undetectable in this study and was not demonstrable even in a solution containing 25,000 mg per litres of crude powder.

Antifertility effect of andrographis paniculata in mice.

Antifertility effect of Andrographis Paniculata was observed in mice under different experimental conditions and control mice continued to give birth to litters of usual size and number for subsequent six matings.

Controlled clinical study of standardized Andrographis paniculata extract in common cold - a pilot trial.

Screening of indigenous plants for anthelmintic action against human Ascaris lumbricoides: Part--II.

  • R. K. Raj
  • Biology, Medicine
    Indian journal of physiology and pharmacology
  • 1975
Alcoholic extracts of the rhizomes of Alpinia galanga, Andrographis paniculata, bark of Cinnamomum zeylanicum, rind of Citrus decumana, Desmodium triflorum, seeds of Hydnocarpus wightiana and rhizome of Kaempfaria galanga showed good in vitro anthelmintic activity against human Ascaris lumbricoides.

Prevention of common colds with Andrographis paniculata dried extract. A Pilot double blind trial.

Andrographolide protects rat hepatocytes against paracetamol-induced damage.

Antithrombotic effects of Andrographis paniculata nees in preventing myocardial infarction.

TFAP might promote the synthesis of PGI2, inhibit the production of TXA2, stimulate the synthesisof cAMP in platelets, impede aggregation of platelet aggregation, and thereby prevent the formation of thrombi as well as the development of myocardial infarction.

Antihepatotoxic effects of major diterpenoid constituents of Andrographis paniculata.