Androgens stimulate endothelial progenitor cells through an androgen receptor-mediated pathway.

@article{Foresta2008AndrogensSE,
  title={Androgens stimulate endothelial progenitor cells through an androgen receptor-mediated pathway.},
  author={C Foresta and Daniela Zuccarello and Luca De Toni and Andrea Garolla and Nicola Caretta and Alberto Ferlin},
  journal={Clinical endocrinology},
  year={2008},
  volume={68 2},
  pages={284-9}
}
BACKGROUND AND OBJECTIVE Testosterone (T) treatment has recently been shown to induce an increase in the number of endothelial progenitor cells (EPCs) through a possible effect on bone marrow. Hypogonadotrophic hypogonadal (HH) men have low circulating EPCs that increase significantly after T treatment. Moreover, expression of the androgen receptor (AR) has been demonstrated by immunohistochemistry in these cells, suggesting that T might also have a direct effect on EPC function. In the present… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 53 extracted citations

Androgen receptor in human endothelial cells.

The Journal of endocrinology • 2015
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…