Androgens regulate MMPs and the cellular processes of intimal hyperplasia.

Abstract

BACKGROUND Testosterone deficiency has been associated with an increased risk of vascular disease. Matrix metalloproteinases (MMPs) have been implicated in vascular remodeling. Our group has demonstrated an association between female hormones and MMP-modulated intimal hyperplasia. In the present study, we investigated testosterone in the modulation of MMPs… (More)
DOI: 10.1016/j.jss.2013.05.070

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