Androgens in women: Hormone-modulating therapies for skin disease.

  title={Androgens in women: Hormone-modulating therapies for skin disease.},
  author={Sarah Azarchi and Amanda Bienenfeld and Kristen I. Lo Sicco and Shari Marchbein and Jerry Shapiro and Arielle R. Nagler},
  journal={Journal of the American Academy of Dermatology},
  volume={80 6},

Understanding Hormonal Therapies: Overview for the Dermatologist Focused on Hair

The specific properties of current estrogen- and progesterone-containing hormonal treatments and their implications for the patient with hair loss are reviewed.

Spironolactone in dermatology: uses in acne and beyond

Treatment with spironolactone aims to attenuate androgen‐mediated conditions including acne, hidradenitis suppurativa, female pattern hair loss and hirsutism.

Effective treatment of skin and metabolic manifestations of hyperandrogenism: a comprehensive improvement of quality of life

The role of combined oral contraceptives (COCs) as an effective therapy for acne and hirsutism in women, as well as the first-line therapy for polycystic ovary syndrome, according to the international and national clinical guidelines are shown.

Spironolactone in Dermatology: Uses in Acne, Hidradenitis Suppurativa, Female Pattern Hair Loss, and Hirsutism

Female Androgenetic Alopecia: An Update on Diagnosis and Management

An update on FAGA is provided and a guideline on diagnosis and management of this frequent hair disease, not always easily recognizable from cicatricial alopecias with a similar distribution is created.

The Role of Finasteride in the Management of Androgenetic Alopecia in Male: A Narrative Review

Finasteride inhibits 5α-reductase and reduce the biosynthesis of dihydrotestosterone (DHT) and provides a novel and selective approach to androgen deprivation.

A systematic review of the effect of platelet‐rich plasma on androgenetic alopecia of women

According to the limited studies included in this systematic review, PRP treatment had a positive effect on the improvement of AGA, increasing hair density, and improving hair diameter in affected women.

Spironolactone and XPB: An Old Drug with a New Molecular Target

The ability of SP to promote cancer stem cell death and facilitate immune recognition may counteract the negative consequences ofSP to mitigate carcinogenic risk.



Hormonal therapies for acne.

Acne: hormonal concepts and therapy.

A review of hormonal therapy for female pattern (androgenic) alopecia.

The role and place of anti-androgentic agents in female androgenetic alopecia in both pre and post-menopausal women remains to be fully defined and the need for effective agents is highlighted by the paucity of effective treatments and the substantial psychosocial impact of alopECia on women.

Spironolactone versus placebo or in combination with steroids for hirsutism and/or acne.

Six months treatment with 100 mg spironolactone compared with placebo was associated with a statistically significant subjective improvement in hair growth and a decrease in Ferriman-Galwey scores, and the effectiveness of treatment for acne vulgaris cannot be determined.

Combined oral contraceptives for the treatment of acne: a practical guide.

Current issues regarding the hormonal treatment of acne in the form of combined oral contraceptives (COCs) are presented, and a practical method for implementing this therapy is proposed.

Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia.

In postmenopausal women with AGA, finasteride 1 mg/day taken for 12 months did not not increase hair growth or slow the progression of hair thinning.

Androgenetic Alopecia: An Update of Treatment Options

The current treatment alternatives for androgenetic alopecia including their efficacy, safety profile, and quality of evidence are discussed.

Androgenetic Alopecia: An Evidence-Based Treatment Update

An assessment of the evidence quality of current publications indicates that oral finasteride and topical minoxidil are the best treatments of androgenetic alopecia.