Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions

@article{Dubois2011AndrogensAS,
  title={Androgens and skeletal muscle: cellular and molecular action mechanisms underlying the anabolic actions},
  author={V. Dubois and M. Laurent and S. Boonen and D. Vanderschueren and F. Claessens},
  journal={Cellular and Molecular Life Sciences},
  year={2011},
  volume={69},
  pages={1651-1667}
}
Androgens increase both the size and strength of skeletal muscle via diverse mechanisms. The aim of this review is to discuss the different cellular targets of androgens in skeletal muscle as well as the respective androgen actions in these cells leading to changes in proliferation, myogenic differentiation, and protein metabolism. Androgens bind and activate a specific nuclear receptor which will directly affect the transcription of target genes. These genes encode muscle-specific… Expand
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  • V. Dubois, M. Laurent, +10 authors F. Claessens
  • Biology, Medicine
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology
  • 2014
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