Androgens and insulin--two key players in polycystic ovary syndrome. Recent concepts in the pathophysiology and genetics of polycystic ovary syndrome.

@article{Schuring2008AndrogensAI,
  title={Androgens and insulin--two key players in polycystic ovary syndrome. Recent concepts in the pathophysiology and genetics of polycystic ovary syndrome.},
  author={Andreas N Schuring and Nicole Schulte and Barbara Sonntag and Ludwig Kiesel},
  journal={Gynakologisch-geburtshilfliche Rundschau},
  year={2008},
  volume={48 1},
  pages={9-15}
}
Androgens and insulin are endocrine key players in the pathophysiology of polycystic ovary syndrome (PCOS), a heterogenic condition of unexplained etiology and a suspected genetic background. Androgens mediate the clinical phenotype of the disease. Therefore,all criteria of the recent PCOS consensus definition are based on their biological effects. Insulin resistance, followed by compensatory hyperinsulinemia, is frequently found in patients with PCOS. Insulin resistance is correlated with a… CONTINUE READING

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The CAG repeat polymorphism influences the phenotype of polycystic ovary syndrome (PCOS)

AN Schüring, A Jürgens, J Gromoll, E Nieschlag, L Kiesel
J Soc Gynecol Invest • 2006

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