Androgenetic Alopecia: An Update of Treatment Options

  title={Androgenetic Alopecia: An Update of Treatment Options},
  author={Yanna Kelly and A. Blanco and Antonella Tosti},
Androgenetic alopecia (AGA) is characterized by a non-scarring progressive miniaturization of the hair follicle in predisposed men and women with a pattern distribution. Although AGA is a very prevalent condition, approved therapeutic options are limited. This article discusses the current treatment alternatives including their efficacy, safety profile, and quality of evidence. Finasteride and minoxidil for male androgenetic alopecia and minoxidil for female androgenetic alopecia still are the… 
Тіе Modern treatment of androgenetic alopecia
Growth factors and cytokines, topical 5-alpha-reductase inhibitors, androgen receptor antagonists, prostaglandin analogs and antagonists, Wnt signaling activators and platelet-rich plasma injections are discussed.
Treat androgenetic alopecia with antiandrogens, as well as other pharmacological and non-pharmacological interventions
Evidence is still poor for the majority of treatment options, including widely-used and new therapies; further studies are needed to provide good-quality evidence for their efficacy and safety.
Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
Treating androgenetic alopecia therapy remains challenging as treatment selection involves ethical, evidence-based decision-making and consideration of each individual patient's needs, compliance, budget, extent of hair loss, and aesthetic goals, independent of potential financial benefits to the practitioners.
Androgenetic Alopecia in Gender Minority Patients.
LITERATURE REVIEW Update Treatment of Male Androgenetic Alopecia
The MAGA therapy is expected to achieve cosmetically significant regrowth and to slow additional hair loss and to affect patients’ quality of life and self-esteem.
The Importance of Vitamin-D in Androgenic Alopecia and Telogen Effluvium
The level of 25’(OH) vit D was found high in androgenic alopecia group than telogen effluvium and controls, and revealing the relationship between vitamin-D level and hair loss might give the opportunity to come up with new treatment options considering refractory patients.
Androgenetic alopecia; drug safety and therapeutic strategies
It is argued that finasteride should be preferred to dutasteride in the treatment of AGA because it preserves important physiological roles of dihydrotestosterone (unrelated to AGA) and, in addition, its adverse effects seem to be (at least in part) predictable.
Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways
An in-depth analysis of PRP in the treatment of androgenetic alopecia is provided based on the evaluation of 17 recent clinical trials published between 2018 and October 2021 to provide an overall consensus on how PRP can be best utilized.
An overview of herbal alternatives in androgenetic alopecia
This article focuses on herbs which can be used in AGA and the role of herbal drugs to have the action against 5‐alpha‐reductase enzyme inhibiting it and reducing the hair loss.
Female patients with androgenetic alopecia: immunohistochemical picture of scalp biopsies
The data obtained by this study helps to improve the concept of morphogenesis of AGA, and also can become a base for improving the standards of treatment of the disease.


Novel treatment of female-pattern androgenetic alopecia with injected bimatoprost 0.03% solution.
Critical points to consider in the future of prostaglandin analogs, as well as other therapies being considered for the treatment of female-pattern hair loss, are suggested.
Characteristics of Androgenetic Alopecia in Asian
Prevalence, hair loss patterns, familial factors, androgen receptor gene polymorphisms of Asian AGA patients, and management based on algorithmic guidelines for AGA are discussed.
Evidence‐based (S3) guideline for the treatment of androgenetic alopecia in women and in men
Androgenetic alopecia is the most common hair loss disorder, affecting both men and women and its frequency increases with age and affects up to 80 % Caucasian men and 42 % of women.
Finasteride induced Gynecomastia: Case report and Review of the Literature
Two cases of gynecomastia are reported, one of them bilateral, caused by Propecia® prescribed for the treatment of androgenetic alopecia, although relatively rare.
Effective treatment of female androgenic alopecia with dutasteride.
Dihydrotestosterone is the main molecule responsible for androgenic alopecia. Finasteride, which reduces transformation of testosterone into dihydrotestosterone and decreases dihydrotestosterone
Antiandrogen therapy for androgenetic alopecia
While these agents are highly effective at preventing hair loss and most patients experience some regrowth, few patients experience dramatic hair regrowth.
Response to Microneedling Treatment in Men with Androgenetic Alopecia Who Failed to Respond to Conventional Therapy
This is the first case series to report the boosting effect of microneedling with respect to new hair follicle stimulation in patients with androgenetic alopecia who were poor responders to conventional therapy.
Female pattern alopecia and telogen effluvium: figuring out diffuse alopecia.
How to distinguish between and properly manage female pattern alopecia, telogen effluvium, or both, as they can coexist is highlighted.
Reversal of androgenetic alopecia by topical ketoconzole: relevance of anti-androgenic activity.