Androgenetic Alopecia: An Update of Treatment Options

@article{Kelly2016AndrogeneticAA,
  title={Androgenetic Alopecia: An Update of Treatment Options},
  author={Yanna Kelly and A. Blanco and Antonella Tosti},
  journal={Drugs},
  year={2016},
  volume={76},
  pages={1349-1364}
}
Androgenetic alopecia (AGA) is characterized by a non-scarring progressive miniaturization of the hair follicle in predisposed men and women with a pattern distribution. Although AGA is a very prevalent condition, approved therapeutic options are limited. This article discusses the current treatment alternatives including their efficacy, safety profile, and quality of evidence. Finasteride and minoxidil for male androgenetic alopecia and minoxidil for female androgenetic alopecia still are the… 
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105 Citations
Highly Influential Citations
4
Background Citations
26
Methods Citations
2

105 Citations

Тіе Modern treatment of androgenetic alopecia
TLDR
Growth factors and cytokines, topical 5-alpha-reductase inhibitors, androgen receptor antagonists, prostaglandin analogs and antagonists, Wnt signaling activators and platelet-rich plasma injections are discussed.
Treat androgenetic alopecia with antiandrogens, as well as other pharmacological and non-pharmacological interventions
TLDR
Evidence is still poor for the majority of treatment options, including widely-used and new therapies; further studies are needed to provide good-quality evidence for their efficacy and safety.
Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.
TLDR
Treating androgenetic alopecia therapy remains challenging as treatment selection involves ethical, evidence-based decision-making and consideration of each individual patient's needs, compliance, budget, extent of hair loss, and aesthetic goals, independent of potential financial benefits to the practitioners.
Androgenetic Alopecia in Gender Minority Patients.
LITERATURE REVIEW Update Treatment of Male Androgenetic Alopecia
TLDR
The MAGA therapy is expected to achieve cosmetically significant regrowth and to slow additional hair loss and to affect patients’ quality of life and self-esteem.
The Importance of Vitamin-D in Androgenic Alopecia and Telogen Effluvium
TLDR
The level of 25’(OH) vit D was found high in androgenic alopecia group than telogen effluvium and controls, and revealing the relationship between vitamin-D level and hair loss might give the opportunity to come up with new treatment options considering refractory patients.
Androgenetic alopecia; drug safety and therapeutic strategies
TLDR
It is argued that finasteride should be preferred to dutasteride in the treatment of AGA because it preserves important physiological roles of dihydrotestosterone (unrelated to AGA) and, in addition, its adverse effects seem to be (at least in part) predictable.
Treatment of Androgenetic Alopecia Using PRP to Target Dysregulated Mechanisms and Pathways
TLDR
An in-depth analysis of PRP in the treatment of androgenetic alopecia is provided based on the evaluation of 17 recent clinical trials published between 2018 and October 2021 to provide an overall consensus on how PRP can be best utilized.
An overview of herbal alternatives in androgenetic alopecia
TLDR
This article focuses on herbs which can be used in AGA and the role of herbal drugs to have the action against 5‐alpha‐reductase enzyme inhibiting it and reducing the hair loss.
Female patients with androgenetic alopecia: immunohistochemical picture of scalp biopsies
TLDR
The data obtained by this study helps to improve the concept of morphogenesis of AGA, and also can become a base for improving the standards of treatment of the disease.
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